Detecting Cancer When the First Cell Appears

Pharmaco-Kinesis Corporation has developed an implantable pump for localized cancer-fighting drug delivery. This first-generation Nano-Impedance Biosensor (NIB) detects vascular endothelial growth factor (VEGF-165) which is a biomarker correlating to the presence of a cancerous tumor in the body. The NIB is about the size of an aspirin and can detect VEGF at levels as low as 1 to 10 protein molecules in the billions of molecules present in 1 mL of body fluid. Products using NIB technology could ultimately become available over-the-counter to enable patients to measure biomarkers for cancer and other chronic illnesses. One can envision implantable sensors to track brain natriuretic peptide or troponin to enable instant therapy delivery for cardiovascular patients.

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